Rohan Shirwaiker

Rohan Shirwaiker is an ISE Professor, Pleasant ISE Faculty Scholar, a University Faculty Scholar, and an Associate faculty member of the UNC-NCSU Joint Department of Biomedical Engineering. He is also the Associate Director of the Functional Tissue Engineering Program at the Comparative Medicine Institute (CMI).

Shirwaiker’s 3D Tissue Manufacturing research group focuses on advancing the science and technology for scalable manufacturing of engineered tissues. They study the fundamental relationships between 3D biofabrication processes, biomaterials, and critical-to-quality attributes of engineered tissues, and develop new tissue manufacturing strategies and platforms. Shirwaiker’s research is highly multidisciplinary and collaborative and has been supported by over $2.5 million in research grants from the National Science Foundation (NSF), Orthopaedic Research and Education Foundation (OREF), and Advanced Regenerative Manufacturing Institute (ARMI), and other funding agencies. He has co-authored over 100 journal articles, conference proceedings and book chapters, and has 3 patents on biomedical devices and processing technologies. He has been recognized by several awards including the NSF CAREER Award, SME Outstanding Young Manufacturing Engineer Award, SME Distinguished Faculty Advisor Award, IISE Manufacturing & Design Outstanding Young Investigator Award, and C. A. Anderson Outstanding Faculty Award.

Shirwaiker teaches undergraduate and graduate courses related to design and manufacturing, including ISE 316 (Manufacturing Engineering I: Processes), ISE 498 (Senior Design Project), ISE 589 (Intro to Biomedical Design and Manufacturing), and ISE 714 (Product Manufacturing for Medical Device Industry). He is the faculty advisor of the SME student chapter at NC State. He serves on the advisory committees of IISE’s Manufacturing & Design division and SME’s North American Manufacturing Research Institution and is a Program Chair of the 2020 IISE Annual Conference.

Publications

Investigating dielectric spectroscopy and soft sensing for nondestructive quality assessment of engineered tissues
Shohan, S., Zeng, Y., Chen, X., Jin, R., & Shirwaiker, R. (2022), BIOSENSORS & BIOELECTRONICS, ["216"], [""]. https://doi.org/10.1016/j.bios.2022.114286
Multiphase CFD Modeling and Experimental Validation of Polymer and Attenuating Air Jet Interactions in Nonwoven Annular Melt Blowing
Schuchard, K. G., Pawar, A., Anderson, B., Pourdeyhimi, B., & Shirwaiker, R. A. (2022), INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, ["61"](37), ["13962–13971"]. https://doi.org/10.1021/acs.iecr.2c01710
Multiscale Anisotropic Tissue Biofabrication via Bulk Acoustic Patterning of Cells and Functional Additives in Hybrid Bioinks
Chansoria, P., Asif, S., Gupta, N., Piedrahita, J., & Shirwaiker, R. A. (2022, January 27), ADVANCED HEALTHCARE MATERIALS, Vol. 1, p. [""]. https://doi.org/10.1002/adhm.202102351
Biofabricated 3D in vitro model of fibrosis-induced abnormal hepatoblast/biliary progenitors' expansion of the developing liver
Brovold, M., Keller, D., Devarasetty, M., Dominijanni, A., Shirwaiker, R., & Soker, S. (2021, June 5), BIOENGINEERING & TRANSLATIONAL MEDICINE, Vol. 12, p. [""]. https://doi.org/10.1002/btm2.10207
Cell-Laden Nanocellulose/Chitosan-Based Bioinks for 3D Bioprinting and Enhanced Osteogenic Cell Differentiation
Maturavongsadit, P., Narayanan, L. K., Chansoria, P., Shirwaiker, R., & Benhabbour, S. R. (2021), ACS APPLIED BIO MATERIALS, 4(3), 2342–2353. https://doi.org/10.1021/acsabm.0c01108
Characterizing the Effects of Synergistic Thermal and Photo-Cross-Linking during Biofabrication on the Structural and Functional Properties of Gelatin Methacryloyl (GeIMA) Hydrogels
Chansoria, P., Asif, S., Polkoff, K., Chung, J., Piedrahita, J. A., & Shirwaiker, R. A. (2021), ACS BIOMATERIALS SCIENCE & ENGINEERING, ["7"](11), ["5175–5188"]. https://doi.org/10.1021/acsbiomaterials.1c00635
Fabrication of drug-loaded ultrafine polymer fibers via solution blowing and their drug release kinetics
Schuchard, K., Joijode, A., Willard, V. P., Anderson, B., Grondin, P., Pourdeyhimi, B., & Shirwaiker, R. (2021), 49TH SME NORTH AMERICAN MANUFACTURING RESEARCH CONFERENCE (NAMRC 49, 2021), pp. ["128–135"]. https://doi.org/10.1016/j.promfg.2021.06.017
Non-destructive quality monitoring of 3D printed tissue scaffolds via dielectric impedance spectroscopy and supervised machine learning
Shohan, S., Harm, J., Hasan, M., Starly, B., & Shirwaiker, R. (2021), 49TH SME NORTH AMERICAN MANUFACTURING RESEARCH CONFERENCE (NAMRC 49, 2021), pp. ["636–643"]. https://doi.org/10.1016/j.promfg.2021.06.063
Steroid eluting biocompatible stent for subglottic stenosis
Manzi, B., Shirwaiker, R., Gungor, A., & Weinberger, P. (2021), EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY. https://doi.org/10.1007/s00405-020-06562-y
The evaluation of a multiphasic 3D-bioplotted scaffold seeded with adipose derived stem cells to repair osteochondral defects in a porcine model
Nordberg, R. C., Huebner, P., Schuchard, K. G., Mellor, L. F., Shirwaiker, R. A., Loboa, E. G., & Spang, J. T. (2021, June 10), JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vol. 6, p. [""]. https://doi.org/10.1002/jbm.b.34886

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Rohan Shirwaiker