Marie Muller

Associate Professor

  • 919-515-1186
  • Engineering Building III (EB3) 3166
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Dr. Muller is interested in medical ultrasound and ultrasound propagation in complex media.  Her long-term objective is to advance the state-of-the-art of medical ultrasound and contribute to screening and prevention methods.

Her  research attracts students because of its high societal impact, because it involves both theory and the learning about state-of-the-art numerical and experimental methods, and because it involves teamwork and collaborations with physicians, physicists and engineers. Since her research is multidisciplinary, students in her lab have the opportunity to tailor their graduate experience to their particular interests. Her applications involve developing non-invasive methods to quantitatively characterize the microstructure of complex biological media such as lung and bone. This leads to the development of new technologies for the diagnosis and monitoring of osteoporosis, pulmonary fibrosis, and pulmonary edema.

Outside of work, she enjoys family, friends, music and food.

Education

Ph.D. 2006

Physical Acoustics

Paris Diderot University

B.S. 2002

Physics

Pierre et Marie Curie University

Research Description

The focus of Dr. Muller's research is on the development of new sources of imaging contrasts that provide diagnostically relevant information. Her approach is based on understanding the propagation of ultrasound and elastic waves in biological tissue, and to establish quantitative relationships between ultrasound parameters and the microarchitecture of tissue. Ongoing research in my lab addresses bone, soft tissue and porous materials. The projects include: (1) Bone microarchitecture modelling and assessment; (2) Characterizing vascular networks; (3) The fundamentals of multiple scattering in tissue.

Grants

Novel Ultrasonic Methods for the Assessment of Pulmonary Edema
National Institutes of Health (NIH)(9/01/20 - 8/31/21)
Novel Ultrasound Localization of Pulmonary Nodules during Video Assisted Thoracic Surgery to Improve Surgical Resection
National Institutes of Health (NIH)(5/15/19 - 4/30/21)
Innovative ultrasonic methods for the diagnosis and monitoring of pulmonary fibrosis
US Dept. of Defense (DOD)(4/15/18 - 4/14/21)
Ultrasound Enhanced Platelet-like Particle Therapy for Accelerated Wound Repair
National Institutes of Health (NIH)(7/17/17 - 6/30/20)
Assessment of Bone Micro-Structure using Ultrasonic Methods
National Institutes of Health (NIH)(8/02/16 - 5/31/19)
Ultrasonic Characterization of Atherosclerotic Plaque using Multiple Scattering
National Institutes of Health (NIH)(9/30/16 - 7/31/19)
Experimental Ultrasonic Characterization of Bone Micro-Architecture
NCSU Faculty Research & Professional Development Fund(7/01/15 - 6/30/16)
Quantitative Characterization of Trabecular Bone Micro-Architecture Using Ultrasound – Applications to the Diagnosis and Monitoring of Spaceflight Osteopenia.
NCSU NC Space Grant Consortium(7/01/15 - 6/30/16)