Jingjie Hu

Assistant Professor

Dr. Jingjie Hu’s research focuses on the mechanical behavior of biomedical and biological materials. Her work contributes to this understanding by focusing on the design, fabrication and characterization of bio related structures through integrated mechanics, materials and bioengineering approaches. It combines experimental and theoretical tools that enable the prediction of mechanical behaviors at the nano-, micro- and macro- scales. Dr. Hu’s research is highly interdisciplinary and impacts critical biomedical applications such as cancer detection and vascular embolization.
Dr. Hu received her Ph.D. from Princeton University and her B.S.E. from the University of Michigan, both in mechanical engineering. Prior to joining NC State, she completed her postdoctoral training in translational bioengineering at Mayo Clinic.

Publications

Characterization of an Injectable Chitosan Hydrogel for the Tunable, Localized Delivery of Immunotherapeutics
Mantooth, S. M., Hancock, A. M., Thompson, P. M., Varghese, P. J. G., Meritet, D. M., Vrabel, M. R., … Zaharoff, D. A. (2024), ACS BIOMATERIALS SCIENCE & ENGINEERING, 10(2), 905–920. https://doi.org/10.1021/acsbiomaterials.3c01580
Chitosan-nanoclay embolic material for catheter-directed arterial embolization
Varghese, P. J. G., Zhao, K., Chen, P., & Hu, J. (2024, January 16), JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol. 1. https://doi.org/10.1002/jbm.a.37670
Developing a transcatheter injectable nanoclay- alginate gel for minimally invasive procedures
Zhao, K., Varghese, P. J. G., Chen, P., & Hu, J. (2024), JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 152. https://doi.org/10.1016/j.jmbbm.2024.106448
Triptorelin-functionalized PEG-coated biosynthesized gold nanoparticles: Effects of receptor-ligand interactions on adhesion to triple negative breast cancer cells
Uzonwanne, V. O., Navabi, A., Obayemi, J. D., Hu, J., Salifu, A. A., Ghahremani, S., … Soboyejo, W. (2022), Biomaterials Advances, 4, 212801. https://doi.org/10.1016/j.bioadv.2022.212801
Actin cytoskeletal structure and the statistical variations of the mechanical properties of non-tumorigenic breast and triple-negative breast cancer cells
Onwudiwe, K., Hu, J., Obayemi, J., Uzonwanne, V., Ani, C., Nwazojie, C., … Soboyejo, W. (2021), Journal of the Mechanical Behavior of Biomedical Materials, 119, 104505. https://doi.org/10.1016/j.jmbbm.2021.104505
Investigation of creep properties and the cytoskeletal structures of non-tumorigenic breast cells and triple-negative breast cancer cells
Onwudiwe, K., Obayemi, J., Hu, J., Oparah, J., Onyekanne, C., Nwazojie, C., … Soboyejo, W. (2021, December 29), JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol. 110. https://doi.org/10.1002/jbm.a.37348
Percutaneous liquid ablation agent for tumor treatment and drug delivery
Albadawi, H., Zhang, Z., Altun, I., Hu, J., Jamal, L., Ibsen, K. N., … Oklu, R. (2021), Science Translational Medicine, 13(580). https://doi.org/10.1126/scitranslmed.abe3889
Silk Embolic Material for Catheter‐Directed Endovascular Drug Delivery
Hu, J., Albadawi, H., Zhang, Z., Salomao, M. A., Gunduz, S., Rehman, S., … Oklu, R. (2021), Advanced Materials, 11, 2106865. https://doi.org/10.1002/adma.202106865
Bioactive‐Tissue‐Derived Nanocomposite Hydrogel for Permanent Arterial Embolization and Enhanced Vascular Healing
Hu, J., Altun, I., Zhang, Z., Albadawi, H., Salomao, M. A., Mayer, J. L., … Oklu, R. (2020), Advanced Materials. https://doi.org/10.1002/adma.202002611
Blood‐Derived Biomaterial for Catheter‐Directed Arterial Embolization
Altun, I., Hu, J., Albadawi, H., Zhang, Z., Salomao, M. A., Mayer, J. L., … Oklu, R. (2020), Advanced Materials. https://doi.org/10.1002/adma.202005603

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Jingjie Hu