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MAE Seminar: Cellular Level Injury Mechanisms of the Brain
April 9 @ 10:00 am - 11:00 am
Brain Injury may occur when brain is exposed to traumatic forces such as blast and concussion that set the matters inside the brain into rapid acceleration and deceleration. The internal structures of brain tissue are highly heterogeneous and hierarchical in nature, and are built on over 150 billion fibrous neuron and glial cells. As such, when the skull is set into motion, the corresponding material motions inside the brain locally vary and may induce normal and shear deformations in the neuron cells. In addition, the interior and exterior regions of neuron cells contain ionic fluids (ECM). The ions can transmit in and out of neuron cells through specific channels located within the cell membranes. The movement of ions across neural membranes alters charge balance across the membrane enabling neuron to rapidly send electrical signals to its neighboring cells and communicate with each other. In this seminar, our recent multiscale computational studies on the mechanical and electric responses of neuron cells due to traumatic forces will be presented. The probable connection between head trauma and damages in neuron cells will be discussed.
Dr. Ashfaq Adnan is a professor in the Mechanical & Aerospace Engineering Department and director of the Multi-scale Mechanics and Physics Lab (MMPL) at UTA. He earned his PhD in Aeronautics & Astronautics Engineering from Purdue University. Before joining UTA in the Fall of 2010, he was a postdoctoral research associate at Northwestern University. His current research on brain injury and neuron damage is funded by multiple Office of Naval Research and Defense University Research Instrumentation Program (DURIP). Dr. Adnan is also a member of an Interdisciplinary Research Hub called PANTHER that focuses on the understanding, detection and prevention of traumatic brain injuries. He is an ASME fellow and the recipient of 2020 Lockheed Martin Teaching Award.
Join Zoom Meeting https://ncsu.zoom.us/j/95825733659
Meeting ID: 958 2573 3659