Research Projects

Research Conducted in the CM-P Lab

At CM-PL, three major research projects are being conducted under the umbrella of “Computational Fluid-Particle Dynamics and Fluid-Structure Interactions,” all involving momentum, mass and heat transfer. The experimentally validated simulation results generate new physical insight which may lead to new theories with suitable mathematical models. The fundamental research work spawns practical applications via device design and prototyping in virtual reality. Examples include (with the help of experimentalists and research MDs) a smart inhaler system (US patent # 7,900,625), a micro-catheter for radioactive particle targeting of tumors (PCT/US application), AAA-rupture-risk-prediction software (Kleinstreuer & Li, 2007), micro-cooling device analysis (Kleinstreuer & Li, 2008), and bio-MEMS for nanomedicinedelivery (Li & Kleinstreuer, 2008).

One overall goal is the development of a patient-specific interaction paradigm for both optimal drug targeting and implant optimization. Clearly, the theoretical part of paradigm implementation requires massive parallel computing for realistic and accurate simulations and ultimately optimal medical device operations.


Lung Aerosol Dynamics, Particle-Hemodynamics, and Nanofluid Flow


aerosols_clip_image022 Lung Aerosol Dynamics, Smart Inhaler Design, and Drug Aerosol Delivery



Particle-Hemodynamics and Tumor Targeting



Nanofluid Flow, Micro-Heat Sinks, and Nanomedicine Delivery

Selected Publication Record